Research Scientist/Engineer 2

Company: University of Washington
Location: Seattle
Posted on: October 12, 2024

Job Description:

If you are using a screen reader and experience any difficulty accessing our web pages, please call 206-543-2544 or email UWHires and we will be happy to assist you.Benefits: As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our website.As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem-solving skills and dedication to build stronger minds and a healthier world.The Department of Pharmacology currently has an outstanding opportunity for a Research Scientist/Engineer 2.Under the general direction of the PI, this position provides comprehensive research to develop novel bioassays to validate potential protein targets for drug development, and for the evaluation of potential disease modifying agents using in vitro bioassays as well as in vivo in the study of breast cancer and Cushing's syndrome.DUTIES AND RESPONSIBILITIES

• 60% - In vitro and In vivo work:
• Perform molecular biology techniques (i.e. PCR, DNA isolation/sequencing), mammalian cell culture, protein biochemistry and pharmacological cell signaling assays.
• Identify and evaluate the roles of novel compounds for regulating in vitro phenotypes using modern cell signaling assays.
• Contribute to the design and execution of cell and tissue-based studies to investigate biological mechanisms of breast cancer and Cushing's syndrome.
• Supervise management of mouse colony.
• Prepare experimental reagents.
• 20% - Data analysis and presentation:
• Keep detailed records.
• Analyze and interpret data.
• Perform regular presentations of data to the research group.
• 15% - Administrative:
• Become aware of lab safety procedures.
• Write and update IACUC protocols for experiments.
• Liaison for regulatory agencies including IACUC and DEA.
• Perform budget management including tracking and forecasting.
• 5% - Training:
• Training and directing other lab members including RSEs, graduate and undergraduate students.MINIMUM REQUIREMENTS
• Bachelor of Science degree in Biology, Biochemistry, Molecular Biology or related field.
• Minimum two years experience or an equivalent education and experience.ADDITIONAL REQUIREMENTS
• Experience performing Cell and/or tissue-based studies including migration and proliferation assays.
• In vivo experience using mouse disease models.
• Experience with management of mouse colonies.
• Experience performing molecular biology techniques.DESIRED QUALIFICATIONS
• Experience performing protein biochemistry techniques.
• Experience with lentiviral mammalian gene expression vectors.
• Experience with Microscopy.
• Must be able to learn budget management including tracking and forecasting.Application Process: The application process may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select "Apply to this position". Once you begin an assessment, it must be completed at that time; if you do not complete the assessment, you will be prompted to do so the next time you access your "My Jobs" page. If you select to take it later, it will appear on your "My Jobs" page to take when you are access ready.
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Keywords: University of Washington, South Hill , Research Scientist/Engineer 2, Engineering , Seattle, Washington